Slc13a2^tm1Smch
Targeted Allele Detail

Summary

• Symbol: Slc13a2^tm1Smch
• Name: solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 2; targeted mutation 1, Stephen Chung
• MGI ID: MGI:4360396
• Synonyms: NaDC1^-
• Gene: Slc13a2 Location: Chr11:78288102-78313107 bp, - strand Genetic Position: Chr11, 46.74 cM
• Alliance: Slc13a2^tm1Smch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152740
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 6 were replaced with a neo cassette. The absence of transcript expression was confirmed by northen blot analysis on kidney extracts and RT-PCR on kidney and small intestine extracts. (J:152740)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc13a2 Mutation: 43 strains or lines available

References

• Original: J:152740 Ho HT, et al., Generation and characterization of sodium-dicarboxylate cotransporter-deficient mice. Kidney Int. 2007 Jul;72(1):63-71
• All: 2 reference(s)