Tg(Col1a1-Atf4)1Kry
Transgene Detail

Summary

• Symbol: Tg(Col1a1-Atf4)1Kry
• Name: transgene insertion 1, Gerard Karsenty
• MGI ID: MGI:4360488
• Synonyms: alpha1(I) Collagen-Atf4
• Transgene: Tg(Col1a1-Atf4)1Kry Location: unknown
• Alliance: Tg(Col1a1-Atf4)1Kry page

Decrease in islet insulin content in Tg(Col1a1-Atf4)1Kry/0 pancreas

Show the 1 phenotype image(s) involving this allele.

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Col1a1-Atf4)1Kry expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Atf4 (MGI:88096)

• Mutation details: 2.3 kb of the promoter drives osteoblast-specific expression of the mouse gene. No line information was provided. (J:129752)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:129752 Elefteriou F, et al., ATF4 mediation of NF1 functions in osteoblast reveals a nutritional basis for congenital skeletal dysplasiae. Cell Metab. 2006 Dec;4(6):441-51
• All: 2 reference(s)