Nipal3^tm1Pbfd
Targeted Allele Detail

Summary

• Symbol: Nipal3^tm1Pbfd
• Name: NIPA-like domain containing 3; targeted mutation 1, Peter Burfeind
• MGI ID: MGI:4360699
• Synonyms: Npal3^-
• Gene: Nipal3 Location: Chr4:135173454-135222283 bp, - strand Genetic Position: Chr4, 67.64 cM, cytoband D3
• Alliance: Nipal3^tm1Pbfd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152829
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 3 through 8 were replaced with a neo cassette. The absence of transcript expression was confirmed by northern blot analysis on brain extracts. (J:152829)

Expression

In Mice Carrying this Mutation:	1 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nipal3 Mutation: 43 strains or lines available

References

• Original: J:152829 Grzmil P, et al., Targeted disruption of the mouse Npal3 gene leads to deficits in behavior, increased IgE levels, and impaired lung function. Cytogenet Genome Res. 2009;125(3):186-200
• All: 2 reference(s)