Tg(Krt19-Wnt1)2Maos
Transgene Detail

Summary

• Symbol: Tg(Krt19-Wnt1)2Maos
• Name: transgene insertion 2, Masanobu Oshima
• MGI ID: MGI:4361187
• Synonyms: K19-Wnt1
• Transgene: Tg(Krt19-Wnt1)2Maos Location: unknown
• Alliance: Tg(Krt19-Wnt1)2Maos page

Transgene origin

• Strain of Origin: (C3H x C57BL/6)F1

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Krt19-Wnt1)2Maos expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Wnt1 (MGI:98953)

• Mutation details: The mouse promoter drives expression of the mouse cDNA in the epithelial cells of gastric mucosa. Five lines were created (lines 1 through 5). Line 2 was selected as the representative line. (J:116782)

Disease models

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Tumor Data

List all tumor models in MMHCdb carrying Tg(Krt19-Wnt1)2Maos

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:116782 Oshima H, et al., Carcinogenesis in mouse stomach by simultaneous activation of the Wnt signaling and prostaglandin E2 pathway. Gastroenterology. 2006 Oct;131(4):1086-95
• All: 12 reference(s)