Peli1^tm1Tigm
Targeted Allele Detail

Summary

• Symbol: Peli1^tm1Tigm
• Name: pellino 1; targeted mutation 1, Texas A&M Institute for Genomic Medicine
• MGI ID: MGI:4361448
• Gene: Peli1 Location: Chr11:21041291-21100323 bp, + strand Genetic Position: Chr11, 13.81 cM, cytoband A3.2
• Alliance: Peli1^tm1Tigm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152781
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 1 and 2 were replaced with a lacZ/neo cassette. The absence of full-length transcript expression was confirmed by RT-PCR. (J:152781)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Peli1 Mutation: 31 strains or lines available

References

• Original: J:152781 Chang M, et al., Peli1 facilitates TRIF-dependent Toll-like receptor signaling and proinflammatory cytokine production. Nat Immunol. 2009 Oct;10(10):1089-95
• All: 12 reference(s)