Tg(Adora2a-cre)KG139Gsat
Transgene Detail

Summary

• Symbol: Tg(Adora2a-cre)KG139Gsat
• Name: transgene insertion KG139, GENSAT Project at Rockefeller University
• MGI ID: MGI:4361654
• Synonyms: A2a-cre, KG139
• Transgene: Tg(Adora2a-cre)KG139Gsat Location: unknown Genetic Position: Chr4, Syntenic
• Alliance: Tg(Adora2a-cre)KG139Gsat page

Transgene origin

• Strain of Origin: FVB/N
• Project Collection: GENSAT

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Adora2a-cre)KG139Gsat expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Adora2a (MGI:99402)

• Mutation details: This transgene contains the coding sequence for Cre recombinase, followed by the SV40 polyadenylation signal to terminate the fusion transcript immediately after the recombinase gene, inserted into the mouse genomic bacterial artificial chromosome (BAC) RP24-238K3 at the ATG transcription initiation codon of the adenosine A2a receptor gene (Adora2a) so that expression of the reporter mRNA/protein is driven by the regulatory sequences of the mouse gene. (J:145110)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Adora2a (mouse) Summary of all recombinase alleles driven by Adora2a. Alliance mouse Adora2a gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available

References

• Original: J:145110 Gong S, et al., Targeting Cre recombinase to specific neuron populations with bacterial artificial chromosome constructs. J Neurosci. 2007 Sep 12;27(37):9817-23
• All: 177 reference(s)