Tg(Aire-cre)1Mnt
Transgene Detail

Summary

• Symbol: Tg(Aire-cre)1Mnt
• Name: transgene insertion 1, Massimo Trucco
• MGI ID: MGI:4361672
• Synonyms: Aire-Cre
• Transgene: Tg(Aire-cre)1Mnt Location: unknown
• Alliance: Tg(Aire-cre)1Mnt page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Aire-cre)1Mnt expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Aire (MGI:1338803)

• Mutation details: The putative transcription regulatory element of the mouse Aire gene was used to drive expression of cre recombinase. The linearized construct was injected into fertilized C57BL/6 oocytes. Two transgenic founders were generated and one was selected for further study. (J:152798)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Aire (mouse) Summary of all recombinase alleles driven by Aire. Comparative matrix view of recombinase activities Alliance mouse Aire gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:152798 Fan Y, et al., Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J. 2009 Sep 16;28(18):2812-24
• All: 2 reference(s)