Ins2^tm1.1Mnt
Targeted Allele Detail

Summary

• Symbol: Ins2^tm1.1Mnt
• Name: insulin II; targeted mutation 1.1, Massimo Trucco
• MGI ID: MGI:4361695
• Synonyms: Ins2^-
• Gene: Ins2 Location: Chr7:142232393-142233463 bp, - strand Genetic Position: Chr7, 88.0 cM
• Alliance: Ins2^tm1.1Mnt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152798
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Mice expressing the Ins2^tm1Mnt allele were crossed to Tg(EIIa-cre)C5379Lgmd mice to delete the Ins2 gene in the germline. (J:152798)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ins2 Mutation: 93 strains or lines available

References

• Original: J:152798 Fan Y, et al., Thymus-specific deletion of insulin induces autoimmune diabetes. EMBO J. 2009 Sep 16;28(18):2812-24
• All: 1 reference(s)