Tg(Gfap-gp120)16Lms
Transgene Detail
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| Symbol: |
Tg(Gfap-gp120)16Lms |
| Name: |
transgene insertion 16, Lennart Mucke |
| MGI ID: |
MGI:4361818 |
| Transgene: |
Tg(Gfap-gp120)16Lms Location: unknown
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| Alliance: |
Tg(Gfap-gp120)16Lms page
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| Strain of Origin: |
C57BL/6 x SJL
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Mutation details: The env gene from the LAV strtain of HIV-1 was truncated to encode gp120 amino acids 1-509 and inserted in exon 1 of a modified murine Gfap gene. Five lines (2, 3,10, 16, 37) were established which varied in level of expression. Level of expression did not correlate with transgene copy number. This is a low expressor line.
(J:146427)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:146427 Toggas SM, et al., Central nervous system damage produced by expression of the HIV-1 coat protein gp120 in transgenic mice. Nature. 1994 Jan 13;367(6459):188-93 |
| All: |
2 reference(s) |
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Analysis Tools
