Per2^tm1.1Kry
Targeted Allele Detail

Summary

• Symbol: Per2^tm1.1Kry
• Name: period circadian clock 2; targeted mutation 1.1, Gerard Karsenty
• MGI ID: MGI:4362035
• Synonyms: Per2^lox(ex10-12)
• Gene: Per2 Location: Chr1:91343699-91387028 bp, - strand Genetic Position: Chr1, 46.13 cM, cytoband C5
• Alliance: Per2^tm1.1Kry page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:115188
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 10 and a floxed neo cassette was inserted downstream of exon 12 via homologous recombination. The neo cassette was then removed by Cre mediated recombination leaving exons 10 - 12 floxed. (J:115188)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Per2 Mutation: 73 strains or lines available

References

• Original: J:115188 Fu L, et al., The molecular clock mediates leptin-regulated bone formation. Cell. 2005 Sep 9;122(5):803-15
• All: 1 reference(s)