Sphk2^tm1.1Stlp
Targeted Allele Detail

Summary

• Symbol: Sphk2^tm1.1Stlp
• Name: sphingosine kinase 2; targeted mutation 1.1, Stanford L Peng
• MGI ID: MGI:4362092
• Synonyms: Sphk2^-
• Gene: Sphk2 Location: Chr7:45358891-45367426 bp, - strand Genetic Position: Chr7, 29.45 cM
• Alliance: Sphk2^tm1.1Stlp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153014
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Exons 4-7 of the gene were removed following Cre-mediated excision. No data are provided. (J:153014)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sphk2 Mutation: 38 strains or lines available

References

• Original: J:153014 Samy ET, et al., Cutting edge: Modulation of intestinal autoimmunity and IL-2 signaling by sphingosine kinase 2 independent of sphingosine 1-phosphate. J Immunol. 2007 Nov 1;179(9):5644-8
• All: 1 reference(s)