Gpr55^tm1.1Mijr
Targeted Allele Detail

Summary

• Symbol: Gpr55^tm1.1Mijr
• Name: G protein-coupled receptor 55; targeted mutation 1.1, Michael J Rogers
• MGI ID: MGI:4365395
• Gene: Gpr55 Location: Chr1:85866039-85888729 bp, - strand Genetic Position: Chr1, 43.94 cM
• Alliance: Gpr55^tm1.1Mijr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153225
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a floxed neo cassette that was subsequently removed by germ line, cre mediated recombination. (J:153225)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpr55 Mutation: 20 strains or lines available

References

• Original: J:153225 Whyte LS, et al., The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo. Proc Natl Acad Sci U S A. 2009 Sep 22;106(38):16511-6
• All: 2 reference(s)