Mmp10^tm1Jkmg
Targeted Allele Detail

Summary

• Symbol: Mmp10^tm1Jkmg
• Name: matrix metallopeptidase 10; targeted mutation 1, John K McGuire
• MGI ID: MGI:4365989
• Gene: Mmp10 Location: Chr9:7502353-7510241 bp, + strand Genetic Position: Chr9, 2.46 cM
• Alliance: Mmp10^tm1Jkmg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153651
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Exons 3 through 5 were replaced with a neo cassette. (J:153651)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mmp10 Mutation: 37 strains or lines available

References

• Original: J:153651 Kassim SY, et al., Individual matrix metalloproteinases control distinct transcriptional responses in airway epithelial cells infected with Pseudomonas aeruginosa. Infect Immun. 2007 Dec;75(12):5640-50
• All: 15 reference(s)