Gprasp1^tm1Ics
Targeted Allele Detail

Summary

• Symbol: Gprasp1^tm1Ics
• Name: G protein-coupled receptor associated sorting protein 1; targeted mutation 1, Mouse Clinical Institute
• MGI ID: MGI:4365990
• Gene: Gprasp1 Location: ChrX:134643482-134704223 bp, + strand Genetic Position: ChrX, 57.26 cM, cytoband F1
• Alliance: Gprasp1^tm1Ics page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153526
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 5 through 11 were replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:153526)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gprasp1 Mutation: 30 strains or lines available

References

• Original: J:153526 Boeuf J, et al., Attenuated behavioural responses to acute and chronic cocaine in GASP-1-deficient mice. Eur J Neurosci. 2009 Sep;30(5):860-8
• All: 2 reference(s)