Tg(KRT14-Ptgs2)1Sumf
Transgene Detail

Summary

• Symbol: Tg(KRT14-Ptgs2)1Sumf
• Name: transgene insertion 1, Susan M Fischer
• MGI ID: MGI:4366345
• Synonyms: K14.COX2
• Transgene: Tg(KRT14-Ptgs2)1Sumf Location: unknown
• Alliance: Tg(KRT14-Ptgs2)1Sumf page

Transgene origin

• Strain of Origin: (C57BL/6 x DBA/2)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(KRT14-Ptgs2)1Sumf expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Ptgs2 (MGI:97798)

• Mutation details: The human promoter was used to drive skin-specific expression of the mouse gene with a 5' beta-globin intron and a 3' SV polyadenylation tail. Two lines were created and the higher expressing one was used as the representative line. (J:76200)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:76200 Bol DK, et al., Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development. Cancer Res. 2002 May 1;62(9):2516-21
• All: 3 reference(s)