Ocm^tm1.1Ddsi
Targeted Allele Detail

Summary

• Symbol: Ocm^tm1.1Ddsi
• Name: oncomodulin; targeted mutation 1.1, Dwayne Simmons
• MGI ID: MGI:4366443
• Gene: Ocm Location: Chr5:143956622-143963488 bp, - strand Genetic Position: Chr5, 82.85 cM, cytoband G1-3
• Alliance: Ocm^tm1.1Ddsi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231626
• Parent Cell Line: SCC10 (ES Cell)
• Strain of Origin: 129X1/SvJ

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele was generated by crossing a Ocm^tm1Ddsi homozygous mouse with a mouse expressing Cre recombinase ubiquitously from a beta-actin promoter. Exons two through four have been deleted from the endogenous gene. (J:231626)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ocm Mutation: 9 strains or lines available

References

• Original: J:231626 Tong B, et al., Oncomodulin, an EF-Hand Ca2+ Buffer, Is Critical for Maintaining Cochlear Function in Mice. J Neurosci. 2016 Feb 3;36(5):1631-5
• All: 4 reference(s)