Gt(ROSA)26Sor^tm6Dym
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^tm6Dym
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 6, Susan Dymecki
• MGI ID: MGI:4366498
• Synonyms: mch/lox/GFP, RC::Epe
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^tm6Dym page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153743
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: The locus was modified to contain a floxed mCherry coding region followed by a GFP coding region. Cre mediated expression is necessary to achieve GFP expression. Expression of mCherry and GFP is mutually exclusive. (J:153473)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 992 strains or lines available

References

• Original: J:153743 Purcell P, et al., Temporomandibular joint formation requires two distinct hedgehog-dependent steps. Proc Natl Acad Sci U S A. 2009 Oct 27;106(43):18297-302
• All: 10 reference(s)