Prdm1^tm1.1Liz
Targeted Allele Detail

Summary

• Symbol: Prdm1^tm1.1Liz
• Name: PR domain containing 1, with ZNF domain; targeted mutation 1.1, Elizabeth K Bikoff
• MGI ID: MGI:4366868
• Synonyms: Prdm1^deltaex1A
• Gene: Prdm1 Location: Chr10:44313173-44404497 bp, - strand Genetic Position: Chr10, 23.24 cM
• Alliance: Prdm1^tm1.1Liz page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153979
• Parent Cell Line: CCE/EK.CCE (ES Cell)
• Strain of Origin: 129S/SvEv-Gpi1^c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1A was replaced with a floxed neo cassette. Transient cre expression in ES cells removed the neo cassette. (J:153979)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Prdm1 Mutation: 66 strains or lines available

References

• Original: J:153979 Morgan MA, et al., Blimp-1/Prdm1 alternative promoter usage during mouse development and plasma cell differentiation. Mol Cell Biol. 2009 Nov;29(21):5813-27
• All: 3 reference(s)