Meig1^tm1.1Zzha
Targeted Allele Detail

Summary

• Symbol: Meig1^tm1.1Zzha
• Name: meiosis expressed gene 1; targeted mutation 1.1, Zhibing Zhang
• MGI ID: MGI:4367077
• Synonyms: Meig1^flox
• Gene: Meig1 Location: Chr2:3410080-3423685 bp, - strand Genetic Position: Chr2, 1.92 cM
• Alliance: Meig1^tm1.1Zzha page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153677
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 1, and an frt flanked neo cassette with a 3' loxP site downstream of exon 1. Germ line, flp mediated recombination removed the neo cassette leaving exon 1 floxed. (J:153677)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meig1 Mutation: 14 strains or lines available

References

• Original: J:153677 Zhang Z, et al., MEIG1 is essential for spermiogenesis in mice. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17055-60
• All: 2 reference(s)