Meig1^tm1.2Zzha
Targeted Allele Detail

Summary

• Symbol: Meig1^tm1.2Zzha
• Name: meiosis expressed gene 1; targeted mutation 1.2, Zhibing Zhang
• MGI ID: MGI:4367078
• Gene: Meig1 Location: Chr2:3410080-3423685 bp, - strand Genetic Position: Chr2, 1.92 cM
• Alliance: Meig1^tm1.2Zzha page

Sperm abnormalities in Meig1^tm1.2Zzha/Meig1^tm1.2Zzha mice

Show the 2 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153677
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination removed exon 1. The absence of protein expression was confirmed by western blot analysis on testes extracts. (J:153677)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Meig1 Mutation: 14 strains or lines available

References

• Original: J:153677 Zhang Z, et al., MEIG1 is essential for spermiogenesis in mice. Proc Natl Acad Sci U S A. 2009 Oct 6;106(40):17055-60
• All: 4 reference(s)