Gt(ROSA)26Sor^{tm2.1(sb11)Njen}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm2.1(sb11)Njen}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 2.1, Nancy A Jenkins
• MGI ID: MGI:4367092
• Synonyms: RosaSBase^1loxP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm2.1(sb11)Njen} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:153656
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6J x 129

Mutation description

• Allele Type: Targeted (Transposase)
• Mutation: Insertion
• Mutation details: Germ line, cre mediated removal of the floxed EGFP and STOP cassette allows for expression of sleeping beauty (sb11) transposase. (J:153656)

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^{tm2.1(sb11)Njen}

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:153656 Dupuy AJ, et al., A modified sleeping beauty transposon system that can be used to model a wide variety of human cancers in mice. Cancer Res. 2009 Oct 15;69(20):8150-6
• All: 2 reference(s)