Dlst^Gt1Lex
Gene trapped Allele Detail

Summary

• Symbol: Dlst^Gt1Lex
• Name: dihydrolipoamide S-succinyltransferase; gene trap 1, Lexicon Genetics
• MGI ID: MGI:4367457
• Gene: Dlst Location: Chr12:85157597-85180865 bp, + strand Genetic Position: Chr12, 39.55 cM, cytoband D3
• Alliance: Dlst^Gt1Lex page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:152550
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S5/SvEvBrd
• Project Collection: Lexicon

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector
• No description available. (J:152550)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dlst Mutation: 17 strains or lines available

References

• Original: J:152550 Dumont M, et al., Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition. Free Radic Biol Med. 2009 Oct 1;47(7):1019-27
• All: 4 reference(s)