S1pr5^tm1Jch
Targeted Allele Detail

Summary

• Symbol: S1pr5^tm1Jch
• Name: sphingosine-1-phosphate receptor 5; targeted mutation 1, Jerold Chun
• MGI ID: MGI:4368002
• Synonyms: S1P5^-
• Gene: S1pr5 Location: Chr9:21154213-21159739 bp, - strand Genetic Position: Chr9, 7.75 cM, cytoband A4
• Alliance: S1pr5^tm1Jch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154069
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

Allele Type: Targeted (Null/knockout, Reporter) Mutations: Insertion, Intragenic deletion Mutation details: Coding sequence for all but the first seven amino acid was replaced with a DsRed gene and a neo cassette. The absence of transcript expression was confirmed by RT-PCR analysis on spinal cord extracts. (J:154069)

Generation of the S1pr5^tm1Jch allele

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any S1pr5 Mutation: 22 strains or lines available

References

• Original: J:154069 Jenne CN, et al., T-bet-dependent S1P5 expression in NK cells promotes egress from lymph nodes and bone marrow. J Exp Med. 2009 Oct 26;206(11):2469-81
• All: 5 reference(s)