Ilk^tm4.1Ref
Targeted Allele Detail

Summary

• Symbol: Ilk^tm4.1Ref
• Name: integrin linked kinase; targeted mutation 4.1, Reinhard Fassler
• MGI ID: MGI:4368006
• Synonyms: E13 loxP
• Gene: Ilk Location: Chr7:105385799-105392132 bp, + strand Genetic Position: Chr7, 55.97 cM, cytoband E1
• Alliance: Ilk^tm4.1Ref page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154054
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Inserted expressed sequence)
• Mutation: Insertion
• Mutation details: A loxP site flanked neomycin resistance gene cassette was inserted into the 3' UTR in exon 13. Cre-mediated recombination removed the neo cassette leaving a single loxP site in exon 13. Transcription is not altered. (J:154054)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ilk Mutation: 18 strains or lines available

References

• Original: J:154054 Lange A, et al., Integrin-linked kinase is an adaptor with essential functions during mouse development. Nature. 2009 Oct 15;461(7266):1002-6
• All: 1 reference(s)