Cep63^{Gt(EUCE0251h11)Hmgu}
Gene trapped Allele Detail

Summary

• Symbol: Cep63^{Gt(EUCE0251h11)Hmgu}
• Name: centrosomal protein 63; gene trap EUCE0251h11, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:4377328
• Synonyms: Cep63^T
• Gene: Cep63 Location: Chr9:102461787-102503733 bp, - strand Genetic Position: Chr9, 54.61 cM
• Alliance: Cep63^{Gt(EUCE0251h11)Hmgu} page

Mutation origin

• Mutant Cell Line: EUCE0251h11
• Germline Transmission: Earliest citation of germline transmission: J:228049
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: rsFlipROSAbgeo*
• Mutation details: A gene-trap cassette inserted between exons 1 and 2 of the gene. PCR analysis, Western blotting and immunofluorescence confirmed that no encoded mRNA or protein was detectable in fibroblast cells isolated from homozygous mice. (J:228049)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  EUCE0251h11.q1k5SPK	FI545411 ; (MGI Seq Detail)	5'Splinkerette PCR	Chr9:102502680-102502954 bp (-)
  EUCE0251h11.p1k3SPK	FI559018 ; (MGI Seq Detail)	3'Splinkerette PCR	Chr9:102502577-102502659 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  24 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Expression

In Structures Affected by this Mutation:

8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cep63 Mutation: 45 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)