Tigar^{Gt(EUCE0047g05)Hmgu}
Gene trapped Allele Detail

Summary

• Symbol: Tigar^{Gt(EUCE0047g05)Hmgu}
• Name: Trp53 induced glycolysis regulatory phosphatase; gene trap EUCE0047g05, Helmholtz Zentrum Muenchen GmbH
• MGI ID: MGI:4391656
• Synonyms: TIGAR^-
• Gene: Tigar Location: Chr6:127062079-127086520 bp, - strand Genetic Position: Chr6, 61.92 cM
• Alliance: Tigar^{Gt(EUCE0047g05)Hmgu} page

Mutation origin

• Mutant Cell Line: EUCE0047g05
• Germline Transmission: Earliest citation of germline transmission: J:198650
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rsFlipROSAbgeo*
• Mutation details: The beta-geo containing gene trap vector inserted upstream of exon 3. Western blot analysis confirmed the absence of protein expression in the liver, heart, muscle, colon, small intestine, thymus, spleen and lung. (J:198650)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  EUCE0047g05.p1k3SPK	FI559658 ; (MGI Seq Detail)	3'Splinkerette PCR	Chr6:127071851-127072251 bp (-)
  EUCE0047g05.q1k5SPK	FI534733 ; (MGI Seq Detail)	5'Splinkerette PCR	multiple
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  71 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tigar Mutation: 58 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)