Ppp1r9a^tm1Pggd
Targeted Allele Detail

Summary

• Symbol: Ppp1r9a^tm1Pggd
• Name: protein phosphatase 1, regulatory subunit 9A; targeted mutation 1, Paul Greengard
• MGI ID: MGI:4397456
• Synonyms: neurabin^-, Nrb^-
• Gene: Ppp1r9a Location: Chr6:4902917-5165661 bp, + strand Genetic Position: Chr6, 1.86 cM, cytoband A1
• Alliance: Ppp1r9a^tm1Pggd page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:110264
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/SvEv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A fragment of 1419 bp of genomic DNA, spanning the complete coding sequence of the first exon, was replaced by an IRESlacZ/MC1neo cassette. Western blot analysis of total brain homogenate confirmed a complete loss of encoded protein expression. (J:110264)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ppp1r9a Mutation: 146 strains or lines available

References

• Original: J:110264 Allen PB, et al., Distinct roles for spinophilin and neurabin in dopamine-mediated plasticity. Neuroscience. 2006 Jul 7;140(3):897-911
• All: 6 reference(s)