Prss21^tm1Anta
Targeted Allele Detail

Summary

• Symbol: Prss21^tm1Anta
• Name: serine protease 21; targeted mutation 1, Toni M Antalis
• MGI ID: MGI:4397679
• Gene: Prss21 Location: Chr17:24087046-24092087 bp, + strand Genetic Position: Chr17, 12.11 cM, cytoband A3.3-B
• Alliance: Prss21^tm1Anta page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154521
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The genomic sequence spanning exon 4, 5, and the coding region of exon 6 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on testis extract. (J:154521)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prss21 Mutation: 14 strains or lines available

References

• Original: J:154521 Netzel-Arnett S, et al., The glycosylphosphatidylinositol-anchored serine protease PRSS21 (testisin) imparts murine epididymal sperm cell maturation and fertilizing ability. Biol Reprod. 2009 Nov;81(5):921-32
• All: 1 reference(s)