Tg(GFAP-EFNA3)181Kln
Transgene Detail

Summary

• Symbol: Tg(GFAP-EFNA3)181Kln
• Name: transgene insertion 181, Rudiger Klein
• MGI ID: MGI:4398695
• Synonyms: Tg181
• Transgene: Tg(GFAP-EFNA3)181Kln Location: unknown
• Alliance: Tg(GFAP-EFNA3)181Kln page

Transgene origin

• Strain of Origin: FVB

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(GFAP-EFNA3)181Kln expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  EFNA3 (1944)

  Efna3

  (MGI:106644)

• Mutation details: The human promoter was used to drive expression of the human cDNA and am N-terminal hemagglutinin tag in glial cells. Two lines were created (line 181 and 7047). Line 181 expresses higher amounts of the transgene than line 7027. (J:154648)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:154648 Filosa A, et al., Neuron-glia communication via EphA4/ephrin-A3 modulates LTP through glial glutamate transport. Nat Neurosci. 2009 Oct;12(10):1285-92
• All: 1 reference(s)