Tfap2e^{tm1.1(cre)Will}
Targeted Allele Detail

Summary

• Symbol: Tfap2e^{tm1.1(cre)Will}
• Name: transcription factor AP-2, epsilon; targeted mutation 1.1, Trevor Williams
• MGI ID: MGI:4398846
• Gene: Tfap2e Location: Chr4:126609799-126630033 bp, - strand Genetic Position: Chr4, 60.91 cM
• Alliance: Tfap2e^{tm1.1(cre)Will} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154236
• Parent Cell Line: CJ7 (ES Cell)
• Strain of Origin: 129S1/Sv-Oca2⁺ Tyr⁺ Kitl⁺

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Tfap2e^{tm1.1(cre)Will} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Tfap2e (MGI:2679630)

• Mutation details: An IRES, cre, and frt flanked neo cassette were inserted into exon 4. Germ line, flp mediated recombination removed the neo cassette. (J:154236)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Tfap2e (mouse) Summary of all recombinase alleles driven by Tfap2e. Alliance mouse Tfap2e gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tfap2e Mutation: 10 strains or lines available

References

• Original: J:154236 Feng W, et al., Disorganized olfactory bulb lamination in mice deficient for transcription factor AP-2epsilon. Mol Cell Neurosci. 2009 Nov;42(3):161-71
• All: 2 reference(s)