Bcl9l^tm1.1Agt
Targeted Allele Detail

Summary

• Symbol: Bcl9l^tm1.1Agt
• Name: B cell CLL/lymphoma 9-like; targeted mutation 1.1, Michel Aguet
• MGI ID: MGI:4398981
• Synonyms: BCL9-2^loxP
• Gene: Bcl9l Location: Chr9:44394122-44423193 bp, + strand Genetic Position: Chr9, 24.84 cM, cytoband B
• Alliance: Bcl9l^tm1.1Agt page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154476
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: Exons 6 and 7 were floxed and the inserted frt flanked neo cassette was removed by germ line, flp mediated recombination. (J:154476)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Bcl9l Mutation: 40 strains or lines available

References

• Original: J:154476 Brack AS, et al., BCL9 is an essential component of canonical Wnt signaling that mediates the differentiation of myogenic progenitors during muscle regeneration. Dev Biol. 2009 Nov 1;335(1):93-105
• All: 8 reference(s)