Omg^tm1.3Bzh
Targeted Allele Detail

Summary

• Symbol: Omg^tm1.3Bzh
• Name: oligodendrocyte myelin glycoprotein; targeted mutation 1.3, Binhai Zheng
• MGI ID: MGI:4399088
• Synonyms: OMgp^CleanNull
• Gene: Omg Location: Chr11:79391808-79394908 bp, - strand Genetic Position: Chr11, 46.79 cM, cytoband B5
• Alliance: Omg^tm1.3Bzh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154794
• Parent Cell Line: AB2.2 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Mutation details: Germ line, cre mediated recombination of Omg^tm1.2 removes exon 2 leaving only frt and loxP site. The absence of protein expression was confirmed by western blot analysis on spinal cord extracts. (J:154794)

Generation of a series of Omg alleles

Expression

In Mice Carrying this Mutation:

8 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Omg Mutation: 20 strains or lines available

References

• Original: J:154794 Lee JK, et al., Generation of an OMgp allelic series in mice. Genesis. 2009 Nov;47(11):751-6
• All: 4 reference(s)