Tcf3tm6(Esr1*)Zhu
Targeted Allele Detail
|
Symbol: |
Tcf3tm6(Esr1*)Zhu |
Name: |
transcription factor 3; targeted mutation 6, Yuan Zhuang |
MGI ID: |
MGI:4399144 |
Synonyms: |
E2AER, Tcf3tm6Zhu |
Gene: |
Tcf3 Location: Chr10:80245348-80269481 bp, - strand Genetic Position: Chr10, 39.72 cM
|
Alliance: |
Tcf3tm6(Esr1*)Zhu page
|
|
Germline Transmission: |
Earliest citation of germline transmission:
J:154788
|
Parent Cell Line: |
Not Specified (ES Cell)
|
Strain of Origin: |
129/Sv
|
|
Allele Type: |
|
Targeted (Inducible) |
Inducer: |
|
tamoxifen |
Mutations: |
|
Insertion, Nucleotide substitutions
|
|
|
Mutation details: The tamoxifen-responsive region from the mouse Esr1 gene with the G525R mutation was inserted at a modified STOP codon in Tcf3tm5Zhu replacing the GFP coding region. A neo cassette was also inserted for selection purposes. Both the E12 and E47 forms contain the modification resulting in tamoxifen-inducible function.
(J:154788)
|
|
Generation of the Tcf3tm6(Esr1*)Zhu allele |
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
|
Carrying any Tcf3 Mutation: |
43 strains or lines available
|
|
Original: |
J:154788 Jones ME, et al., A tamoxifen inducible knock-in allele for investigation of E2A function. BMC Dev Biol. 2009;9:51 |
All: |
2 reference(s) |
|