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Vamp5tm1(KOMP)Vlcg
Targeted Allele Detail
Summary
Symbol: Vamp5tm1(KOMP)Vlcg
Name: vesicle-associated membrane protein 5; targeted mutation 1, Velocigene
MGI ID: MGI:4399506
Gene: Vamp5  Location: Chr6:72345777-72357451 bp, - strand  Genetic Position: Chr6, 32.27 cM, cytoband C3
Alliance: Vamp5tm1(KOMP)Vlcg page
IMPC: Vamp5 gene page
Mutation
origin
Mutant Cell Lines:  13123A-E2, 13123A-E5, 13123A-F3, 13123A-G9
Germline Transmission:  Earliest citation of germline transmission: J:261567
Parent Cell Line:  VGB6 (ES Cell)
Strain of Origin:  C57BL/6NTac
Project Collection: KOMP-Regeneron
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion     Vector: ZEN-Ub1
 
Mutation detailsThe insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 11129bp between positions 72346235-72357363 of Chromosome 6 (Build GRCm39). All exons except the start codon were deleted and replaced with reporter genes. Western blot analysis confirmed the absence of encoded protein in the kidney and bladder of adult homozygous mutant mice. (J:136110, J:261567)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 1 line available
Carrying any Vamp5 Mutation:  18 strains or lines available
References
Original:  J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008;
All:  2 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory