Tmem219^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Tmem219^{tm1(KOMP)Vlcg}
• Name: transmembrane protein 219; targeted mutation 1, Velocigene
• MGI ID: MGI:4399704
• Gene: Tmem219 Location: Chr7:126485343-126522089 bp, - strand Genetic Position: Chr7, 69.25 cM, cytoband F4
• Alliance: Tmem219^{tm1(KOMP)Vlcg} page
• IMPC: Tmem219 gene page

Mutation origin

• Mutant Cell Lines: 13990A-C5, 13990A-D7, 13990A-D11, 13990A-E6, 13990A-E9, 13990A-E11
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 8284bp between positions 126488076-126496359 of Chromosome 7 (Build GRCm39). (J:136110)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Tmem219 Mutation: 10 strains or lines available

Notes

Cell line 13990A-E6 was successfully used to make chimeric mice. Germline transmission was accomplished. J:236976

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 3 reference(s)