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Tg(tetO-Spdef)1Jaw
Transgene Detail
Summary
Symbol: Tg(tetO-Spdef)1Jaw
Name: transgene insertion 1, Jeffrey A Whitsett
MGI ID: MGI:4399759
Synonyms: TRE2-Spdef
Transgene: Tg(tetO-Spdef)1Jaw  Location: unknown  
Alliance: Tg(tetO-Spdef)1Jaw page
Absence of proliferation during goblet cell hyperplasia in Tg(Scgb1a1-rtTA)1Jaw/0 Tg(tetO-Spdef)1Jaw/0 mice

Show the 1 phenotype image(s) involving this allele.

Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe tetracycline response element 2 was used to drive the inducible, lung-specific expression of the mouse gene. Two lines were created (no line names given). (J:121284)
Phenotypes
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Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:121284 Park KS, et al., SPDEF regulates goblet cell hyperplasia in the airway epithelium. J Clin Invest. 2007 Apr;117(4):978-88
All:  9 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory