Fzr1^tm1.2Stge
Targeted Allele Detail

Summary

• Symbol: Fzr1^tm1.2Stge
• Name: fizzy and cell division cycle 20 related 1; targeted mutation 1.2, Stephen Geley
• MGI ID: MGI:4410513
• Gene: Fzr1 Location: Chr10:81202713-81214204 bp, - strand Genetic Position: Chr10, 39.72 cM
• Alliance: Fzr1^tm1.2Stge page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154779
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination of Fzr1^tm1.1Stge removed exons 2 through 8. (J:154779)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Fzr1 Mutation: 43 strains or lines available

References

• Original: J:154779 Sigl R, et al., Loss of the mammalian APC/C activator FZR1 shortens G1 and lengthens S phase but has little effect on exit from mitosis. J Cell Sci. 2009 Nov 15;122(Pt 22):4208-17
• All: 1 reference(s)