Eed^tm1Sho
Targeted Allele Detail

Summary

• Symbol: Eed^tm1Sho
• Name: embryonic ectoderm development; targeted mutation 1, Stuart Orkin
• MGI ID: MGI:4410540
• Synonyms: Eed^flox
• Gene: Eed Location: Chr7:89603862-89630184 bp, - strand Genetic Position: Chr7, 50.42 cM
• Alliance: Eed^tm1Sho page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154730
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S1/Sv

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A targeting vector was designed to insert a loxP site upstream of exon 3, and an FRT-flanked neomycin resistance (neo) cassette was inserted between exons 6 and 7 followed immediately by a second loxP site. (J:154730, J:182226, J:205522)

Expression

In Mice Carrying this Mutation:

24 assay results 13 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Eed Mutation: 116 strains or lines available

References

• Original: J:154730 Yu M, et al., Insights into GATA-1-mediated gene activation versus repression via genome-wide chromatin occupancy analysis. Mol Cell. 2009 Nov 25;36(4):682-95
• All: 44 reference(s)