Gsx2^tm1.1Kc
Targeted Allele Detail

Summary

• Symbol: Gsx2^tm1.1Kc
• Name: GS homeobox 2; targeted mutation 1.1, Kenneth Campbell
• MGI ID: MGI:4412063
• Synonyms: Gsx2^EGFP, Gsx2^GFP-KI
• Gene: Gsx2 Location: Chr5:75236262-75238554 bp, + strand Genetic Position: Chr5, 39.55 cM
• Alliance: Gsx2^tm1.1Kc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:147161
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An IRES-EGFP and frt flanked neo cassette replaces 125 bp of exon 1. Germ line, flp mediated recombination removes the neo cassette. The absence of protein expression was confirmed by immunohistochemistry on the telecephalon. (J:147161)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gsx2 Mutation: 18 strains or lines available

References

• Original: J:147161 Wang B, et al., Ascl1 is a required downstream effector of Gsx gene function in the embryonic mouse telencephalon. Neural Dev. 2009;4:5
• All: 8 reference(s)