About   Help   FAQ
Tg(TetO-Nfkbia*S32A*S36A)1Wcg
Transgene Detail
Summary
Symbol: Tg(TetO-Nfkbia*S32A*S36A)1Wcg
Name: transgene insertion 1, Warner C Greene
MGI ID: MGI:4412273
Synonyms: Tet-O-IkappaBalpha-SR
Transgene: Tg(TetO-Nfkbia*S32A*S36A)1Wcg  Location: unknown  
Alliance: Tg(TetO-Nfkbia*S32A*S36A)1Wcg page
Transgene
origin
Strain of Origin:  DBA
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe Nfkbia gene containing two mutations causing Serine to Alanine changes at codons 32 and 36 (supperrepressor or -SR) was placed under the control of the TetO promoter. Eight founder lines were developed. (J:112973)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:112973 O'Mahony A, et al., NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity. Mol Cell Biol. 2006 Oct;26(19):7283-98
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
11/12/2024
MGI 6.24
The Jackson Laboratory