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Tg(TetO-Nfkbia*S32A*S36A)1Wcg
Transgene Detail
Summary
Symbol: Tg(TetO-Nfkbia*S32A*S36A)1Wcg
Name: transgene insertion 1, Warner C Greene
MGI ID: MGI:4412273
Synonyms: Tet-O-IkappaBalpha-SR
Transgene: Tg(TetO-Nfkbia*S32A*S36A)1Wcg  Location: unknown  
Alliance: Tg(TetO-Nfkbia*S32A*S36A)1Wcg page
Transgene
origin
Strain of Origin:  DBA
Transgene
description
Transgene Type:    Transgenic (Inducible, Inserted expressed sequence)
Inducer:    doxycycline/tetracycline
Mutation:    Insertion
 
Mutation detailsThe Nfkbia gene containing two mutations causing Serine to Alanine changes at codons 32 and 36 (supperrepressor or -SR) was placed under the control of the TetO promoter. Eight founder lines were developed. (J:112973)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:112973 O'Mahony A, et al., NF-kappaB/Rel regulates inhibitory and excitatory neuronal function and synaptic plasticity. Mol Cell Biol. 2006 Oct;26(19):7283-98
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory