Ltbp4^dmod1-DBA/2J
QTL Variant Detail

Summary

• QTL variant: Ltbp4^dmod1-DBA/2J
• Name: latent transforming growth factor beta binding protein 4; DBA/2J
• MGI ID: MGI:4414656
• Synonyms: Ltbp4^d
• QTL: Ltbp4 Location: Chr7:27004561-27037117 bp, - strand Genetic Position: Chr7, 15.87 cM

Variant origin

• Strain of Specimen: DBA/2J

Variant description

• Allele Type: QTL
• Mutation: Intragenic deletion
• Mutation details: A 36 bp deletion removing 12 amino acids shortens the proline rich region of the gene. Strains carrying this deletion include: I/LnJ, BPH/2J, CBA/J, DBA/1J, DBA/2J, MA/MyJ. (J:155107)

References

• Original: J:155107 Heydemann A, et al., Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest. 2009 Dec;119(12):3703-12
• All: 6 reference(s)