Ltbp4^dmod1-r
Allele Detail

Summary

• Symbol: Ltbp4^dmod1-r
• Name: latent transforming growth factor beta binding protein 4; Duchenne modifier 1 resistant
• MGI ID: MGI:4414657
• Synonyms: Ltbp4^{dmod1-129T2/vEmsJ}
• Gene: Ltbp4 Location: Chr7:27004561-27037117 bp, - strand Genetic Position: Chr7, 15.87 cM
• Alliance: Ltbp4^dmod1-r page

Mutation origin

• Strain of Origin: various

Mutation description

• Allele Type: Not Applicable
• Mutation: Insertion
• Mutation details: A 36 bp insertion, encoding for 12 amino acids, extends the proline-rich region of the gene. Strains carrying this insertion include: NZO/HlLtJ, BUB/BnJ, MRL/MpJ, CZECHII/E, MSM/Ms, JF1, CD1, PWD/PhJ, 129S1/SvImJ, 129T2/SvEmsJ, BTBR T<+> tf/J , C57BL/6, C57BL/10. (J:155107)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 10 strains available Cell Lines: 0 lines available
• Carrying any Ltbp4 Mutation: 140 strains or lines available

References

• Original: J:155107 Heydemann A, et al., Latent TGF-beta-binding protein 4 modifies muscular dystrophy in mice. J Clin Invest. 2009 Dec;119(12):3703-12
• All: 3 reference(s)