Myg1^tm1Mphi
Targeted Allele Detail

Summary

• Symbol: Myg1^tm1Mphi
• Name: melanocyte proliferating gene 1; targeted mutation 1, Mari-Anne Philips
• MGI ID: MGI:4414758
• Gene: Myg1 Location: Chr15:102240144-102246574 bp, + strand Genetic Position: Chr15, 57.49 cM
• Alliance: Myg1^tm1Mphi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154911
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A Lac-Z neo cassette replaced a 6.1 kb region immediately following the promoter region and including all 7 exons of the gene. In situ hybridization analysis confirmed the absence of mRNA expression in homozygous embryos. (J:154911)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Myg1 Mutation: 20 strains or lines available

References

• Original: J:154911 Philips MA, et al., Myg1-deficient mice display alterations in stress-induced responses and reduction of sex-dependent behavioural differences. Behav Brain Res. 2010 Feb 11;207(1):182-95
• All: 1 reference(s)