Plec^tm4.1Gwi
Targeted Allele Detail

Summary

• Symbol: Plec^tm4.1Gwi
• Name: plectin; targeted mutation 4.1, Gerhard Wiche
• MGI ID: MGI:4414774
• Synonyms: plec^delta
• Gene: Plec Location: Chr15:76055174-76115578 bp, - strand Genetic Position: Chr15, 35.48 cM
• Alliance: Plec^tm4.1Gwi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155511
• Parent Cell Line: E14.1 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Cre mediated recombination removed exons 26 through 31. (J:155511)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Plec Mutation: 174 strains or lines available

References

• Original: J:155511 Fuchs P, et al., Targeted inactivation of a developmentally regulated neural plectin isoform (plectin 1c) in mice leads to reduced motor nerve conduction velocity. J Biol Chem. 2009 Sep 25;284(39):26502-9
• All: 1 reference(s)