Ate1^tm2.1Akas
Targeted Allele Detail

Summary

• Symbol: Ate1^tm2.1Akas
• Name: arginyltransferase 1; targeted mutation 2.1, Anna Kashina
• MGI ID: MGI:4414839
• Synonyms: Ate1^f
• Gene: Ate1 Location: Chr7:129993223-130122099 bp, - strand Genetic Position: Chr7, 73.19 cM
• Alliance: Ate1^tm2.1Akas page

Ate1^tm2.1Akas/Ate1^tm2.1Akas Tg(Tek-cre)12Flv/0 mice have delayed development and die at early post-implantation stages

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155427
• Parent Cell Line: D1 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6J)F1

Mutation description

Allele Type: Targeted (Conditional ready, No functional change) Mutation: Insertion Mutation details: A loxP site was inserted upstream of exon 1 and an frt flanked neo cassette with a 3' loxP site was inserted downstream of exon 3. Flp mediated recombination removed the neo cassette leaving exons 1 through 3 floxed. (J:155427)

Generation of the Ate1^tm2.1Akas allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ate1 Mutation: 43 strains or lines available

References

• Original: J:155427 Leu NA, et al., Conditional Tek promoter-driven deletion of arginyltransferase in the germ line causes defects in gametogenesis and early embryonic lethality in mice. PLoS One. 2009;4(11):e7734
• All: 9 reference(s)