Wnt8b^tm1Jmas
Targeted Allele Detail

Summary

• Symbol: Wnt8b^tm1Jmas
• Name: wingless-type MMTV integration site family, member 8B; targeted mutation 1, John Mason
• MGI ID: MGI:4414945
• Gene: Wnt8b Location: Chr19:44481912-44502712 bp, + strand Genetic Position: Chr19, 37.98 cM
• Alliance: Wnt8b^tm1Jmas page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155332
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 4 and 5 and most of the coding region contained within exon 6 were replaced with a neo cassette. The absence of transcript expression was confirmed by RT-PCR and in situ hybridization. (J:155332)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wnt8b Mutation: 17 strains or lines available

References

• Original: J:155332 Fotaki V, et al., Loss of Wnt8b has no overt effect on hippocampus development but leads to altered Wnt gene expression levels in dorsomedial telencephalon. Dev Dyn. 2010 Jan;239(1):284-96
• All: 2 reference(s)