Xcl1^tm1Rakr
Targeted Allele Detail

Summary

• Symbol: Xcl1^tm1Rakr
• Name: chemokine (C motif) ligand 1; targeted mutation 1, Richard A Kroczek
• MGI ID: MGI:4415308
• Gene: Xcl1 Location: Chr1:164759216-164763094 bp, - strand Genetic Position: Chr1, 72.26 cM
• Alliance: Xcl1^tm1Rakr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:155297
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 and 3 were replaced with a neo cassette. The absence of protein expression was confirmed by cell staining. (J:155297)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Xcl1 Mutation: 11 strains or lines available

References

• Original: J:155297 Dorner BG, et al., Selective expression of the chemokine receptor XCR1 on cross-presenting dendritic cells determines cooperation with CD8+ T cells. Immunity. 2009 Nov 20;31(5):823-33
• All: 2 reference(s)