Kif26a^tm1.1Noh
Targeted Allele Detail

Summary

• Symbol: Kif26a^tm1.1Noh
• Name: kinesin family member 26A; targeted mutation 1.1, Nobutaka Hirokawa
• MGI ID: MGI:4415314
• Gene: Kif26a Location: Chr12:112112642-112148181 bp, + strand Genetic Position: Chr12, 61.14 cM
• Alliance: Kif26a^tm1.1Noh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:154859
• Parent Cell Line: CMTI-1 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Cre mediated recombination removed exon P and the IRES beta-geo cassette. The absence of protein expression was confirmed by western blot analysis on brain extracts. (J:154859)

Expression

In Mice Carrying this Mutation:	12 assay results
In Structures Affected by this Mutation:	5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kif26a Mutation: 51 strains or lines available

References

• Original: J:154859 Zhou R, et al., KIF26A is an unconventional kinesin and regulates GDNF-Ret signaling in enteric neuronal development. Cell. 2009 Nov 13;139(4):802-13
• All: 2 reference(s)