Rb1^tm2.1Brn
Targeted Allele Detail

Summary

• Symbol: Rb1^tm2.1Brn
• Name: RB transcriptional corepressor 1; targeted mutation 2.1, Anton Berns
• MGI ID: MGI:4415315
• Synonyms: Rb^delta19
• Gene: Rb1 Location: Chr14:73430298-73563446 bp, - strand Genetic Position: Chr14, 38.73 cM, cytoband D3
• Alliance: Rb1^tm2.1Brn page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:77982
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The floxed exon 19 was deleted from Rb1^tm2Brn in the germ line by crossing with an actin-cre deleter strain. (J:77982)

Expression

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rb1 Mutation: 111 strains or lines available

References

• Original: J:77982 Vooijs M, et al., Tumor formation in mice with somatic inactivation of the retinoblastoma gene in interphotoreceptor retinol binding protein-expressing cells. Oncogene. 2002 Jul 11;21(30):4635-45
• All: 1 reference(s)