Lst1^{tm1(KOMP)Vlcg}
Targeted Allele Detail

Summary

• Symbol: Lst1^{tm1(KOMP)Vlcg}
• Name: leukocyte specific transcript 1; targeted mutation 1, Velocigene
• MGI ID: MGI:4415420
• Gene: Lst1 Location: Chr17:35404071-35407415 bp, - strand Genetic Position: Chr17, 18.59 cM
• Alliance: Lst1^{tm1(KOMP)Vlcg} page
• IMPC: Lst1 gene page

Mutation origin

• Mutant Cell Lines: 12118A-A9, 12118A-B1, 12118A-C1, 12118A-H2
• Germline Transmission: Earliest citation of germline transmission: J:204812
• Parent Cell Line: VGB6 (ES Cell)
• Strain of Origin: C57BL/6NTac
• Project Collection: KOMP-Regeneron

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion Vector: ZEN-Ub1
• Mutation details: The insertion of Velocigene cassette ZEN-Ub1 created a deletion of size 3241bp between positions 35404130-35407370 of Chromosome 17 (Build GRCm39). RT-PCR analysis of lung and spleen homogenates confirmed the absence of transcripts in homozygous mutant mice. (J:136110)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 1 line available
• Carrying any Lst1 Mutation: 8 strains or lines available

References

• Original: J:136110 Velocigene, Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals). MGI Direct Data Submission. 2008
• All: 4 reference(s)